Thursday, October 21, 2010

diabetes meds

Pioglitazone, a thiazolidinedione, is a diabetic agent approved for glucose lowering and has been shown to lower triglycerides, raising high-density lipoprotein cholesterol, and lowering the concentration of low-density lipoprotein (LDL) particles.


  • Biguanides (Metformin) tell the liver to produce less glucose and help muscle and fat cells and the liver absorb more glucose from the bloodstream. This lowers blood sugar levels.
  • Sulfonylureas (like glimepiride, glyburide, and tolazamide) trigger the pancreas to make more insulin. They are taken by mouth.
  • Thiazolidinediones (such as rosiglitazone) help muscle and fat cells and the liver absorb more blood sugar when insulin is present. Rosiglitazone may increase the risk of heart problems. Talk to your doctor.
  • Injectible medications (including exenatide and pramlintide) can lower blood sugar.
  • Meglitinides (including repaglinide and nateglinide) trigger the pancreas to make more insulin in response to the level of glucose in the blood.
  • Alpha-glucosidase inhibitors (such as acarbose) decrease the absorption of carbohydrates from the digestive tract to lower after-meal glucose levels.